Abstract

Even in the absence of genetic or environmental differences, cells differ from each other in their molecular make‐up. The consequences of these phenotypic differences are often not well understood. New work by Waite et al () directly links variation in the molecular composition of individual bacterial cells to their population‐level performance.

Highlights

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  • In a recent article published in Molecular Systems Biology, Thierry Emonet and colleagues (Waite et al, 2016) overcame this difficulty by studying the chemotactic swimming behaviour of Escherichia coli bacteria

  • Chemotaxis in E. coli is an ideal model system to map a cell’s phenotype to its performance: the molecular players and their interactions are characterized in great detail, and the swimming behaviour of cells can readily be measured using video microscopy

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