Abstract

Hydrogels have numerous applications in tissue engineering, drug delivery system, and as soft actuators, and then, adhesion of hydrogels has attracted attention because it is one of the simplest processes for building 3D constructs. For the fabrication of on-demand hydrogel materials, a stimulus-responsive adhesive method that can work well under physiological conditions is required. This chapter summarizes adhesion of hydrogels, particularly focusing on electrophoretic adhesion of hydrogels for fabrication of functional 3D materials. Oppositely charged and the same-charged hydrogels adhered to each other by DC and AC electrophoretic adhesion, respectively. Nonionic hydrogel also adhered by combination of AC electrophoretic adhesion and specific interactions. To apply this adhesive method to build a 3D material, the rapid fabrication of hydrogel constructs was achieved by the electrophoretic adhesion of microgel to each other. The electrophoretic adhesion of hydrogels will be useful as powerful method for the fabrication of novel 3D hydrogel constructs by bottom-up technology.

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