Abstract
Smart materials or intelligent or responsive materials are those materials with one or more properties that can be changed in a controlled fashion by surrounding stimuli. Cyclodextrin-based functional systems have grabbed considerable attention for their applications in the biomedical and therapeutic fields due to their unique bioactive properties, selective recognition ability, and excellent biocompatibility. The physicochemical properties of the cyclodextrin-based systems can be altered in the presence of stimuli such as pH, temperature, redox, glutathione and enzyme. This review discusses the current advances in the biomedical and therapeutic applications of stimuli-responsive cyclodextrin-based smart materials.
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