Abstract
Discovery of cisplatin furthered the development of many platinum and non-platinum drugs for anticancer and cell imaging applications. However, non-selective nature of these drugs exert toxicity to both, cancer and normal cells. This review focuses on use of external stimuli viz. UV-light and enzyme nitroreductase to release the drugs specifically in cancer cells to exert anticancer activity as well as release a fluorophore for imaging hypoxic cells.
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