Abstract

The effects of preincubation of human T-lymphoma cells with increasing concentrations of calcium L-threonate on the uptake of L−[1− 14C] ascorbic acid were examined. Calcium L-threonate (0 − 1, 000 mg%) stimulated ascorbic acid (1.25 mg%) uptake in a dose-dependent manner. These results indicate that calcium threonate and possibly other ascorbic acid metabolites have biological activity and potential pharmacological applications.

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