Abstract
Lobster nerves metabolize glucose to a considerable extent via a direct oxidative pathway. The presence of 10 −5 M menadione strongly inhibits anaerobic glycolysis but greatly stimulates oxidative metabolism. Lobster nerves take up sugars from solution. Glucose is taken up readily and continuously for some time; sucrose and mannitol reach equilibrium at a low level and after a short period of time and are not taken up thereafter. Menadione markedly stimulates apparent uptake of glucose but has no effect on mannitol. This stimulation is due to the increased metabolism of glucose. Glucose uptake is also stimulated by removal of Ca ++ and Mg ++ from the medium.
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