Abstract

Background Tooth extraction is generally followed by alveolar ridge resorption that later can cause flat ridge. Aloe vera have biogenic stimulator and hormone activities for wound healing. Purpose This study was aimed to know osteoblast activities in alvaeolar bone after induction of Aloe vera and XCB application. Methods Fifty four of Cavia cabaya were divided into three main groups. Group I was control group. Group II was filled with XCB and group III was filled with the combination of Aloe vera gel and XCB. Then, each group was divided into three sub groups according to timing, they are 14, 30, and 60 days after tooth extraction and application. Histology and morphology examination were performed on the harvested specimens. Results There were significant differences between the control group and the other groups filled with the combination of Aloe vera and xenograft concelous bovine (XCB). Conclusion The application of Aloe vera gel and xenograft decrease the number of osteoclast and increase the number of osteoblast in post tooth extraction alveolar bone structure indicating the new growth of alveolar bone.

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