Abstract
Summary An assessment was made of the efficacy of 5 cholinergic drugs (arecoline, carbachol, neostigmine, physostigmine and pilocarpine) in inducing lachrymation and salivation in 44 adult hens. While the drugs all produced signs of cholinergic stimulation, including secretory activity, the greatest lachrymal response was obtained with neostigmine, and salivation was most copious with carbachol. Inhalation of irritant fumes induced transient lachrymation but various spiced materials applied to the oral mucosa had no significant effect. For routine induction of lachrymation an intramuscular injection of neostigmine (0·3 mg./kg) followed after 10 min. by a similar dose of atropine, is advocated. Salivation can be successfully induced by 0·7 mg./kg. carbachol, atropine being given only when considered necessary.
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