Stimulation of gallbladder emptying and pancreatic secretion in chicks by soybean whey protein.

Abstract

SummaryMany investigators have studied the effects of trypsin and chymoltrypsin inhibitors on the size, enzyme content and enzyme secretion of the pancreas of rats and chicks. In general, these investigations showed that the pancreases of animals fed diets containing sources of proteolytic inhibitors had greater quantities of enzymes after a fast than comparable fasted animals fed control diets (1-5). When pancreatic enzyme levels were measured after animals were fed, those receiving sources of proteolytic inhibitors generally had lower levels of all pancreatic enzymes than animals not receiving the inhibitor (2-4, 6-8). Thus dietary proteolytic inhibitars appear to cause a general stimulation of the pancreas, resulting in both an increased synthesis and a greater secretion of pancreatic enzymes.Trypsin inhibitors from the soybean (6, 9), the navy bean (10), egg white (5, 9), a synthetic inhibitor, p-aminobenzamidine (11), tannins from carobs (12) or peanut skins (13) and a chymotrypsin inhibitor from pot...