Stimulation of Erythropoiesis by Androgenic Hormones.

Abstract

s1 April 1962Stimulation of Erythropoiesis by Androgenic Hormones.B. J. Kennedy, M.D., F.A.C.P.B. J. Kennedy, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-56-4-685_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAndrogenic hormones have been proven to have specific stimulatory effect on erythropoiesis. In patients with advanced breast cancer, the administration of large doses of hormone resulted in an increase in hemoglobin, increase in hematocrit, reticulocytosis, and clinical signs of polycythemia. Extended studies have been performed to define this phenomenon more clearly. Radioactive chromium studies of blood volume and red cell mass have recorded an increase in the red cell mass volume. Bone marrow examinations revealed a hyperplasia of the erythroid elements without alteration of the white cell elements or megakaryocytes. The elevation of the hemoglobin and hematocrit was noted in... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Minneapolis, Minn. (CI) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 April 1962Volume 56, Issue 4Page: 685-685KeywordsBlood cellsBone marrow cellsBreast cancerChromiumErythropoiesisHematocritHemoglobinHormonesMegakaryocytesPolycythemia Issue Published: 1 April 1962 PDF downloadLoading ...