Abstract
There are more and more data suggesting efficacy of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depressions in older patients. Thus, the authors found useful to realize an up-to-date review of studies which examined the efficacy and safety of rTMS to treat depressive disorders in aged. Several parameters might be associated with greater antidepressant efficacy: higher intensity pulses of rTMS of the left dorso latéral préfrontal cortex (DLPFC), 90 to 110% of motor threshold; higher total number of stimulations (more than 1000); higher number of total rTMS sessions (10 to 20). Poorer responsiveness to rTMS may be related to several patients’ factors, including older age and lesions of the central nervous system. Literature data globally confirm that rTMS is safe and does not produce cognitive deficits, even among highly vulnerable patients with clinical evidence of cerebrovascular disease.
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