Abstract
Stimulant use disorder (SUD) is a significant cause of morbidity and mortality around the world. Stimulants are natural and synthetic compounds that include cocaine, methamphetamines, and prescription stimulants. It is very important for providers before prescribing the stimulants to recognize and understand their high potential for addiction, as well as the consequences of withdrawals and chronic use. Amphetamines and cocaine are both stimulants with similar behavioral properties but with differences in their individual mechanism of action and pharmacokinetic properties. There are multiple clinical effects of stimulants but cardiac complications are the most common cause of death. There are multiple modalities for the treatment of SUD, including psychosocial, pharmacologic, and vaccines. Although these treatments are moderately effective, the treatment plan needs to be carefully customized. [ Psychiatr Ann. 2018;48(8):372–378.]
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