Abstract
BackgroundMultiple variables have been studied in relation to health-related quality of life (HRQoL), but research has not integrated the contributions of different variables in a single model that allows to compare them. This study, carried out with people living with HIV/AIDS in India, sought to develop a prediction model considering various predictors previously found to be related to HRQoL, namely sociodemographic factors, HIV symptoms, social support, stigmas and avoidant coping.MethodsA sample of 961 HIV-positive persons from Bengaluru and Mumbai participated in this cross-sectional study, completing a sociodemographic questionnaire along with HRQoL, HIV symptoms, disclosure expectations, disclosure avoidance, social support and internalized, felt, vicarious and enacted stigma scales. Bivariate associations were obtained (correlations, ANOVAs and t tests) and a multiple regression analysis was performed.ResultsResults show that, when all variables are considered together, being married, widowed or deserted, symptom intensity, internalized stigma, disclosure avoidance and enacted stigma contribute negatively to predict HRQoL. On the other hand, being employed, good disclosure expectations and good social support contribute positively to predict HRQoL. Almost half of the variance in HRQoL was explained by this model.ConclusionsInterventions seeking to increase HRQoL in people living with HIV/AIDS in India would benefit from addressing these aspects.
Highlights
Multiple variables have been studied in relation to health-related quality of life (HRQoL), but research has not integrated the contributions of different variables in a single model that allows to compare them
Literature has shown that even when the HIV infection is asymptomatic it has a significant impact on HRQoL [7], which should come as no surprise, as being diagnosed usually leads to a restructuring of People Living with HIV (PLHIV)’s lives
Aims of this paper Our objective is to develop a multiple regression model that considers various predictors previously found to be related to HRQoL, namely some sociodemographic factors, HIV symptoms, social support, stigmas and avoidant coping
Summary
Multiple variables have been studied in relation to health-related quality of life (HRQoL), but research has not integrated the contributions of different variables in a single model that allows to compare them. People Living with HIV (PLHIV) have longer lifespans, which creates new challenges for health care systems. These are shifting the focus from prolonging PLHIV’s lives to improving their quality of life (QoL), especially the healthrelated QoL (HRQoL), which is becoming increasingly important as a therapy outcome [5,6,7] and constitutes a HRQoL refers to those QoL components that refer to physical and mental health [8], and considers biological aspects and psychological and environmental ones [1]. A variety of psychosocial challenges are encountered with regard to personal relationships, financial security, and discrimination, all of which might impact HRQoL [9, 10]
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