Abstract
Cell adhesion molecules (CAM) mediate cell to cell interactions in various body systems including the immune system. The four major families of CAMs include immunoglobulin (Ig) superfamily, cadherins, integrins, and selectins. Most interestingly, several CAMs have emerged in recent years as leading biomarkers of lupus nephritis (LN) based on comprehensive proteomic screens of urine. Proteins belonging to all four families of CAMs have been reported to be upregulated in LN urine
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