Abstract

A 72-year-old woman visited our institution for palliative care. Fifteen years previously, she had undergone a total hysterectomy and radiation therapy for cervical cancer. Since lymphedema progressed even after treatment, lymphaticovenous anastomosis was performed. However, her condition did not improve and although she had discovered a purple ulcerated lesion on her right thigh three years ago, she did not consult a doctor. One year previously, she visited a hospital because of walking disturbance and was diagnosed with lymphangiosarcoma. Neither systemic chemotherapy nor immunotherapy with interleukin-2 was effective. She was confined to bed with massive leg edema, multiple skin ulcerations, and bleeding at the time of admission (Picture 1). Postmortem examination confirmed the diagnosis (Picture 2). Lymphangiosarcoma is a rare malignancy, also called Stewart-Treves syndrome, and occurs in patients with chronic lymphedema (1). Physicians should be aware of this malignancy because surgical removal of the local lesion is the only curable treatment available. The authors state that they have no Conflict of Interest (COI).

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