Abstract

Stevens–Johnson syndrome and toxic epidermal necrolysis in an academic hospital setting: a 5-year retrospective study

Highlights

  • Toxic epidermal necrolysis and Stevens–Johnson syndrome are acute life-threatening mucocutaneous reactions to drugs

  • Toxic epidermal necrolysis (TEN) and Stevens–Johnson syndrome (SJS) are acute life-threatening mucocutaneous reactions usually to drugs characterized by extensive necrosis and detachment of the epidermis plus widespread erythematous or purpuric macules or flat atypical lesions [1] (Fig. 1)

  • The medical records of SJS/TEN patients hospitalized at Department of Dermatology in The Infant Jesus Teaching Hospital in Warsaw, Poland between 2009 and 2014 were retrospectively reviewed

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Summary

INTRODUCTION

Toxic epidermal necrolysis (TEN) and Stevens–Johnson syndrome (SJS) are acute life-threatening mucocutaneous reactions usually to drugs characterized by extensive necrosis and detachment of the epidermis plus widespread erythematous or purpuric macules or flat atypical lesions [1] (Fig. 1). These two conditions are severity variants of an identical process of epidermal necrolysis (EN) that differs only in the final extent of body surface involved: below 10% in SJS, from 10 to 30% in overlap SJS/TEN and above 30% of the body surface in TEN [1,2].

MATERIALS AND METHODS
RESULTS
35‐58 Transfer to ICU
CONCLUSION
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