Abstract
One new C21-steroid, pregnane A (1), and two new anolides daturafolisides X and Y (2 and 3), together with six known with anolides (4–9), were isolated from the roots of Datura metel L. The structures of these compounds were established by 1D and 2D NMR spectra and mass spectroscopy by comparing our results with the literature values. Compounds 1–9 were evaluated for inhibition against nitric oxide production in lipopolysaccharide-induced RAW 264.7 macrophages. It was found that the isolated compounds showed the different levels of anti-inflammatory activities with IC50 values ranging from 24.2 to 43.4 μmol/L.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
