Abstract
Two steroids compounds, 7?-Hydoxy ?-sitosterol (1) and ?-sitosterol (2), have been isolated from ethyl acetate extract of the fresh Super Red Dragon Fruit (Hylocereus costaricensis).The chemical structure of compounds 1 and 2 were identified by spectroscopic data including UV, IR, NMR-1D, NMR-2D and mass as well as by comparing with previously reported spectral data. Compounds 1 and 2 were reported for the first time from dragon fruit (Hylocereus costaricensis).
 Keywords: 7?-Hydoxy ?-sitosterol, ?-sitosterol, Hylocereus costaricensis, steroids.
Highlights
Steroids is an important class of secondary metabolites, widely widespread in plants, animals, marines as well as fungi and have similarity to cholesterol in structure (Saeidnia et al, 2014), including β-sitosterol, campesterol, stigmasterol and cycloartenol (Ostlund, 2002)
The demand for Super Red Dragon Fruit extensively increases and the fruit today can be found on almost all exotic fruit markets around the world (Salakpetch, 2000; Mohd, 2010)
Plant material The fresh fruit of H. costaricensis were collected in Plantation Plant at Cicalengka District, West Java Province, Indonesia in April 2017
Summary
Steroids is an important class of secondary metabolites, widely widespread in plants, animals, marines as well as fungi and have similarity to cholesterol in structure (Saeidnia et al, 2014), including β-sitosterol, campesterol, stigmasterol and cycloartenol (Ostlund, 2002). Especially β-sitosterol was reported to have interesting activity including anti-inflammatory (Prieto et al, 2006), inducing apoptosis (Chai et al, 2008; Park et al, 2007; Ju et al, 2004), chemoprotective or chemopreventive effects (Ovesna et al, 2004), hypocholesterolemic (Zak et al, 1990), angiongenic effect (Moon et al, 1999), anti-diabetic (Gupta et al, 2011; Jamaluddin et al, 1994; Radika et al, 2013), and anti-oxidant (Baskar et al, 2012; Vivancos and Moreno, 2005). Previous phytochemical studies on the species of H. costaricensis have revealed the presence mostly of polyphenolic compounds. Polyphenolic compounds of this species have been investigated previously, the steroid composition of H. costaricensis is yet to be reported. The isolation and structure identification of these isolated compounds are described
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