Abstract
Pemphigus vulgaris (PV) is an autoimmune blistering disease characterized by circulating pathogenic IgG autoantibodies against desmoglein 3 and desmoglein 1. Oral lesions readily rupture, new bullae developing as the older ones rupture and ulcerate. Oral lesions may precede cutaneous lesions in 53.52% cases. Prompt recognition and diagnosis is critical since it may prevent cutaneous involvement. Systemic steroids remain the gold standard treatment of PV. Their use has transformed what was almost invariably a fatal illness into one whose mortality is now below 10%. We report a case of patient with oral ulcers since 4 months, who is diagnosed with PV without cutaneous involvement.
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