Steroid Therapy and Fatal Varicella in a Nephrotic Patient; A Necropsy case with Atypical Rash

Abstract

AbstractIn this paper we present an autopsy case of fatal varicella. The patient was a 14‐year‐old boy who had minimal change nephrotic syndrome. While undergoing treatment with 1.5 mg/kg/day of prednisolone, he developed atypical vesicular lesions and disseminated intravascular coagulation. He died within 3 days of showing signs of varicella. The microscopic tests revealed herpetic viral particles in many organs. When treating nephrotic syndrome with steroids, each individual patient must be taken into consideration and the smallest effective dose should be used for a shorter period.