Abstract
The occurrence of a solitary sternal metastasis from breast cancer is relatively uncommon, and its treatment is controversial. Most case reports on the role of sternal resection in what is termed a "solitary sternal metastasis" tend to present a rather optimistic outcome.Here, we report the case of a premenopausal woman with axillary lymph node-positive, triple-negative breast cancer treated with mastectomy followed by adjuvant chemotherapy and radiation therapy. She developed a radiologically isolated sternal recurrence 3 years later, which was treated with partial sternectomy. The present case report reviews the use of sternectomy for breast cancer recurrence and highlights the need for thorough clinical and radiologic evaluation to ensure the absence of other systemic disease before extensive surgery is undertaken.
Highlights
CASE REPORTA 35-year-old woman with a history of breast cancer diagnosed 3 years earlier was referred to us for discussion of bisphosphonate use after surgical excision of an isolated sternal metastasis
We report the case of a premenopausal woman with axillary lymph node–positive, triple-negative breast cancer treated with mastectomy followed by adjuvant chemotherapy and radiation therapy
A 35-year-old woman with a history of breast cancer diagnosed 3 years earlier was referred to us for discussion of bisphosphonate use after surgical excision of an isolated sternal metastasis. Her initial breast cancer was treated with left mastectomy and axillary node dissection
Summary
A 35-year-old woman with a history of breast cancer diagnosed 3 years earlier was referred to us for discussion of bisphosphonate use after surgical excision of an isolated sternal metastasis. Her initial breast cancer was treated with left mastectomy and axillary node dissection. Immunohistochemistry was negative for estrogen, progesterone, and human epidermal growth factor (HER2/neu) receptors This patient received adjuvant epirubicin/5fluorouracil/cyclophosphamide (FEC-100) chemotherapy for 6 cycles and locoregional radiation treatment. Fine-needle aspiration of the latter node was positive for triple-negative, poorly differentiated invasive ductal carcinoma
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