Sterile Peritonitis Associated with Amino Acid–Containing Dialysate—a Single Center Experience in Norway

Abstract

cases of sterile peritonitis occurred. All Nutrineal bags used for APD came from the same batch; the Extraneal and Physioneal bags came from different batches. The restriction with regard to use of APD and the PEN regimen was lifted after 3 months. The manufacturer (Baxter Healthcare) was notified. The production sites and batches of the dialysis fluids, and the lines and connections, were thoroughly checked for impurities. Neither peptidoglycans nor endotoxins were detected. These were the first cases of Nutrineal-associated peritonitis ever reported. We concluded that impurities in the amino acid–containing fluid were most likely the cause of the sterile peritonitis, but to date and to our knowledge, no specific agent has been identified. DISCLOSURES