Abstract

ABSTRACT Sterigmatocystin (STC) is a possible human carcinogen (2B) according to International Agency for Research on Cancer classification and has been associated with immunotoxic and immunomodulatory activity, together with mutagenic effects. It might be found in numerous substrates, from foods and feeds to chronically damp building materials and indoor dust. Although European Food Safety Authority concluded that the exposure to STC to be of low concern for public health, reinforces the need of data concerning exposure of European citizens. Climate change can represent an increased risk of exposure to STC since it is a crucial factor for agro-ecosystem powering fungal colonisation and mycotoxin production This aspect can represent an increased risk for European countries with temperate climates and it was already reported by the scientific community.

Highlights

  • Food and feed can be contaminated with a mixture of mycotoxins, toxic secondary metabolites produced by fungal species

  • Inoculated onto Dichloran chloramphenicol peptone agar (DCPA); incubated at 25°C for 5–7 days; conidial suspensions inoculated onto Czapek Yeast Extract Agar (CYA), Czapek Yeast Extract Agar CY20S and Malt extract agar (MEA), and incubated in the dark at 25°C for 7–14 days

  • Inoculated onto Dichloran chloramphenicol peptone agar (DCPA); 5–7 days of incubation at 25°C Inoculated onto potato dextrose agar (PDA) ; incubated at 25°C in dark for 7 days

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Summary

Background

Food and feed can be contaminated with a mixture of mycotoxins, toxic secondary metabolites produced by fungal species. Other aspects can influence the profile and levels of the mycotoxins present, namely, industrial processes involved and, after being acquired, household preparation process (Nijs et al 2016). We should consider that mycotoxins are extremely difficult to eliminate from food even after the cooking process because they are quite stable molecules. All this explains why mycotoxins can be present in the food or environment long after death and disintegration of the toxic fungus (Peraica et al 1999; Halstensen 2008; Alborch et al 2011; Viegas et al 2015)

Aspergillus section Versicolores
STC production ability
STC toxicity
Analytical methods
Results
STC toxicokinetics
Toxicity of STC
STC mode of action
Dose–response modelling
Food and feed contamination already reported
Climate change influence on STC production
In 2007 total 120 analysis samples
Future perspectives regarding food and feed contamination
Full Text
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