Abstract
Stereotactic body radiation therapy (SBRT) appears an effective and safe treatment modality for spinal bone metastasis, which can enhance local control and improve quality of life. Life expectation, predicted fracture risk, localization, quality, size and number of metastasis and presence or absence of nerve compression seem to be important factors in decision-making for treatment. Further studies are needed to identify subsets of patient which will most benefit from treatment.
Highlights
Bone metastasis develops in approximately one-third of all patients with cancer
Several methods are used in the treatment of bone metastases, radiotherapy (RT) is more commonly preferred method since it provides faster pain palliation that persists in long-term in most cases and has minimal adverse effects (Price et al, 1988; Chow et al, 2007; Murai et al, 2014)
RT is used for two distinct purposes as either palliative or stereotactic radiotherapy in case of oligometastasis and/or in patients with prolonged life expectation in lieu of surgical approaches (Price et al, 1988; Chow et al, 2007; Murai et al, 2014; De Bari et al, 2015)
Summary
Bone metastasis develops in approximately one-third of all patients with cancer. Bone metastases are important causes of morbidity and mortality in clinical practice and impair quality of life by causing pain, pathological fracture, spinal cord compression, bone marrow failure and sever hypercalcemia. Stereotactic body radiation therapy (SBRT) appears an effective and safe treatment modality for spinal bone metastasis, which can enhance local control and improve quality of life. Several methods are used in the treatment of bone metastases, radiotherapy (RT) is more commonly preferred method since it provides faster pain palliation that persists in long-term in most cases and has minimal adverse effects (Price et al, 1988; Chow et al, 2007; Murai et al, 2014).
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Asian Pacific journal of cancer prevention : APJCP
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
