Abstract
Hepatoma Research is an open access journal and focuses on all topics related to hepatoma. The following articles are especially welcome: pathogenesis, clinical examination and early diagnosis of hepatoma, complications of hepatoma, and their preventions and treatments, etc.
Highlights
Hepatocellular carcinoma (HCC) is one of the most common malignant diseases in the world and the fourth most common cause of cancer death in Japan[1,2]
Laboratory testing, imaging findings, and stereotactic body radiation therapy (SBRT) parameters were extracted from the medical records, and the comorbidities of the patients were evaluated by the Charlson comorbidity index[9]
All the patients were pathologically or radiologically diagnosed with primary liver malignancy; one patient was diagnosed with intrahepatic cholangiocarcinoma, the remainder of patients were diagnosed with HCC
Summary
Hepatocellular carcinoma (HCC) is one of the most common malignant diseases in the world and the fourth most common cause of cancer death in Japan[1,2]. Patients with liver tumors who are referred to SBRT are usually unsuitable for surgery or other local therapies due to comorbidity and impaired liver function. In daily practice, a considerable proportion of tumors are unfit for typical SBRT planning due to the radiation therapy planning dose constraint. Both physical factors and tumor factors affect the decision of treatment choice. The more patient factors that do not meet clinical trial criteria, the higher tendency to select non-localized treatment or conservative options instead of liver SBRT in clinical practice. This study aimed to evaluate the efficacy and feasibility of liver SBRT for cases with originally defined adverse factors
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