Abstract
Abstract— Sulpiride, an unusual neuroleptic, was resolved into its two enantiomers by a newly developed procedure. (‐)Sulpiride is several times more active than (+)sulpiride in increasing rat prolactin secretion and DOPAC concentrations in rat strialum and limbic areas. These results are in agreement with clinical data showing that (‐)sulpiride is the active form of the drug.
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