Stereoselective synthesis of (−)-N-Boc-statine and (−)-N-Boc-Norstatine

G Veeresha,Apurba Datta

doi:10.1016/s0040-4039(97)01108-8

Stereoselective synthesis of (−)-N-Boc-statine and (−)-N-Boc-Norstatine

G Veeresha, Apurba Datta

https://doi.org/10.1016/s0040-4039(97)01108-8

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Journal: Tetrahedron Letters	Publication Date: Jul 1, 1997
Citations: 32

Affiliation: Indian Institute of Chemical Technology

#Vinylmagnesium Bromide #Selective Reaction + Show 2 more

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Abstract

An efficient synthesis of optically pure N-Boc-statine ( 9) and N-Boc-norstatine ( 11) has been developed via a syn selective Grignard reaction of N-Boc-leucinal with allyl- or vinylmagnesium bromide.

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