Abstract
The stereoselective synthesis of isovaline (2-amino-2-methylbutyric acid) and the stereochemical pathway via the key intermediate 2 is described. For use in peptide synthesis, this α,α-dialkyl amino acid is incorporated into N-protected dipeptide derivatives in high yields. Special emphasis was put on the upscaling-problem.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
