Abstract

E-mail: parkyong@konkuk.ac.krReceived November 28, 2005Key Words : Nucleophilic substitution, Asymmetric syntheses, Chiral auxiliary, Peptidomimetics, Dynamickineitc resolutionSince configurational lability of -halo- -alkyl acyl com-pounds is readily induced by a base and/or a halide ion,chiral auxiliary mediated dynamic resolution of -haloesters or -halo amides in nucleophilic substitution has beenrecently recognized as an effective method for asymmetricsyntheses.

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