Abstract
AbstractThe E,Z‐configured 1,3‐diene unit is a common motif in numerous bioactive natural products. Although several powerful methods are available to produce these motifs with high levels of selectivity, their construction within a complex, polyfunctionalised structure, such as a natural product, requires well‐defined strategies to avoid undesirable reactions and low‐to‐moderate selectivities. The aim of this review is to provide a full account of the stereoselective strategies for building E,Z‐configured 1,3‐dienes, as well as to highlight selected total syntheses that employ them.magnified image
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have