Abstract
An efficient cascade protocol for the stereoselective synthesis of borylated carbocycles via copper-catalyzed borylative Michael/Michael cyclization is presented. Using this mild approach, up to 24 new boronic ester substituted indanes, cyclohexanes, and cyclopentanes were prepared in good yields with excellent diasteroselectivities and exceptional functional group tolerance. Furthermore, carbacyclic boronates were oxidized successfully through synthetic transformation. Gram-scale synthesis of the present protocol was also carried out effectively.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
