Abstract

Not all newly created arteriovenous fistulas (AVFs) successfully mature and develop into a functioning access for hemodialysis. Percutaneous transluminal angioplasty (PTA) and balloon-assisted maturation (BAM) have been utilized to either treat flow-limiting stenoses or to promote and accelerate maturation. We hypothesized that unusable upper arm AVFs can be rescued by conversion to a functional access using the percutaneous placement of a stent graft (SG). Clinical data on 12 patients with an early non-usable upper arm AVF underwent percutaneous revision using SGs. There were six brachial-cephalic, three brachial-basilic, and three brachial-brachial vein transposition AVFs. All patients had either at least two or more stenoses (>2 cm) within the fistula conduit, or a long segment stenosis (>4 cm) in combination with shorter segment stenoses. Nine patients had failed PTA. Three patients had failed BAM at outside access centers. All patients were referred for failure to achieve access cannulation and concomitant hemodialysis through the AVF. SGs were placed retrograde toward the arterial anastomoses and ranged in diameter (6, 7, and 8 mm in four, seven, and one patients, respectively). The average length of the SG was 10 cm (range 5-15 cm). All SGs were post-balloon dilated at the time of placement. All AVFs were salvaged, and patients were able to maintain functional use of their access with cannulation occurring through the SG. The primary patency rate at 6 and 12 months was 91% [95% confidence interval (CI), 56-98%] and 65% (95% CI, 32-87%), respectively (n = 11 and 5 at risk, respectively). The secondary patency rate at 6 and 12 months was 100 and 72% (95% CI, 46-93%), respectively (n = 11 and 7 at risk, respectively). This report outlines a successful initial experience using SGs to rescue, preserve, and convert an unusable upper arm AVF into a functioning hemodialysis access.

Highlights

  • A patent functioning hemodialysis access, either graft or fistula, is critical in ensuring effective treatment for patients with end-stage renal disease

  • At the time of presentation, all patients were on hemodialysis through a tunneled dialysis catheter

  • All patients were referred for failure to achieve access cannulation and concomitant hemodialysis through the AV fistulae (AVF)

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Summary

Introduction

A patent functioning hemodialysis access, either graft or fistula, is critical in ensuring effective treatment for patients with end-stage renal disease. The literature on the outcome of the use of stent grafts (SGs) in salvaging failed arteriovenous (AV) accesses is limited. Shemesh and colleagues [6] published a randomized prospective study suggesting that the use of SGs may be superior to bare metal stents for the treatment of cephalic arch stenoses in autogenous AV accesses. The purpose of this case series is to examine the outcome of attempted salvage of early non-usable (primary non-maturation) AV fistulae (AVF) with SGs

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