Abstract
Stem cells are defined as clonogenic self-renewing progenitor cells that can generate into one or more specialized cell types. Stem cells are biological cells found in all multi-cellular organisms that can divide through mitosis and differentiate into diverse specialized cell types and can self renew to produce more stem cells. Self renewal and totipotency are characteristic of stem cells. Though totipotency is shown by very early embryonic stem cells the adult stem cells possess multi-potency and differential plasticity which can be exploited for future generation of therapeutic options. Thus they represent an important building block for regenerative medicine and tissue engineering.Teeth are the most natural non-invasive source of stem cells. Dental stem cells which are easy convenient and affordable to collect hold promise for a range of very potential therapeutic applications. The search for more accessible mesenchymal stem cells MSCs than those found in bone marrow has propelled interest in dental tissues which are rich sources of stem cells. This article provides an overview of stems cells and then focuses on dental stem cells DSCs and how recent developments have the potential to greatly impact the way DSCs might be used in future regenerative medicine applications that include regenerative endodontic therapies.
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