Abstract
Stem Cells: Microenvironment, Micro/Nanotechnology, and Application.
Highlights
Hard tissue damage and loss caused by mechanical trauma, degenerative diseases, infections, tumors, and other diseases exert a profound negative impact on patients’ quality of life and impose a heavy social and economic burden
Being one of the two major hard tissues in the human body, teeth require a wider range of seed cell sources for regeneration compared to bone, that is, stem cells derived from various dental tissues besides bone marrow and embryonic stem cells, such as dental pulp, dental papilla, periodontal ligament, dental follicle, apical papilla, and odontogenic epithelium
Lu et al in the dental field within this special issue showed that odontogenesis of dental pulp stem cells can be tuned by varying the crosslinking of polyethylene glycol-fibrinogen (PF) hydrogel on which the cells were seeded
Summary
Editorial Stem Cells: Microenvironment, Micro/Nanotechnology, and Application Hua Liu,1,2 Zhiyong Zhang,3,4 Wei Seong Toh,5,6 Kee Woei Ng,7 Shilpa Sant,8,9 and António Salgado10 The 3 major elements of tissue engineered constructs are the seeded cells, the scaffolds, and the microenvironment.
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