Abstract
Stem Cells, Inflammation, and Fibrosis.
Highlights
In this special issue of, several research groups contribute with original research articles as well as review articles that provide novel insights about the possible role of stem cells in modulation of inflammation and fibrosis
mesenchymal stem cells (MSCs) produce cytokines, chemokines, and growth factors that robustly regulate cell behavior in a paracrine fashion during the remodeling process. Due to their immunomodulatory effects and their ability to act on profibrotic factors such as oxidative stress, hypoxia, and the transforming growth factor-β1 (TGF-β1) pathway, MSC has already been highlighted in preclinical and clinical studies of inflammatory diseases
MSCs as well as their secretomes have been investigated as a novel therapeutic approach for the treatment of inflammatory and fibrotic diseases in several papers published in this issue
Summary
In this special issue of, several research groups contribute with original research articles as well as review articles that provide novel insights about the possible role of stem cells in modulation of inflammation and fibrosis. 1 Centre for Molecular Medicine and Stem Cell Research, Faculty of Medical Science, University of Kragujevac, 69 Svetozara Markovica Street, 34000 Kragujevac, Serbia 2Institute of Anatomy, University of Bern, Baltzerstrasse 2, 3000
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have