Abstract
Vessel Plus is an open acccess journal, which publishes articles related to vascular diseases, including acute respiratory distress syndrome, aneurysm, atherosclerosis, hypertension, stroke, peripheral vascular or pulmonary vascular diseases, etc.
Highlights
Owing to the aging global population, the socioeconomic burden of stroke is increasing, and stroke has become the second most common cause of death[1]
The majority of clinical trials for stroke have used cultured autologous mesenchymal stem cells (MSCs) derived from bone marrow, adipose tissue, or umbilical cord[10] administered via intravenous transplantation, which is a simple delivery technique that has been approved by government regulations[10]
neural stem cells (NSCs) transplantation in cerebral ischemia may contribute hypoxia-inducible factor-1alpha[39], while the cell-dose dependent effect of NSCs on functional recovery suggests that a high number of stem cells is crucial to ensure adequate neurogenesis and angiogenesis[40]
Summary
Owing to the aging global population, the socioeconomic burden of stroke is increasing, and stroke has become the second most common cause of death[1]. The majority of clinical trials for stroke have used cultured autologous mesenchymal stem cells (MSCs) derived from bone marrow, adipose tissue, or umbilical cord[10] administered via intravenous transplantation, which is a simple delivery technique that has been approved by government regulations[10].
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