Abstract

Human cardiac regeneration therapy has been performed by using various sources of stem cell. Myoblasts and bone marrow cells have been injected for patients with ischemic cardiomyopathy in our clinical trial and improved cardiac performance. We had examined the efficacy of stem cell therapy using tissue engineered sheet technique compared to needle injection. This technique has advantages such as the ability for treatment to large area, and less invasive for host heart such as lethal arrhythmia.

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