Abstract
Limbal stem cell deficiency (LSCD) is a complex ocular condition with difficulty in corneal epithelialization, persistent ep ithelial defects, corneal neovascularization, and corneal conjunctivalization. The reason underlying this condition could be either primary or secondary. Chemical and thermal burns, Stevens-Johnson syndrome, ocular cicatricial pemphigoid, trauma, aniridia, ectodermal dysplasia, and iatrogenic mechanism are in the etiologic scope of the disease. Management of LSCD remains a controversial issue of ophthalmology. There are several treatment alternatives regarding the mechanism of the disease. These options include surface reconstruction with amniotic membrane, autologous and allogeneic limbal stem cell (SC) transplantation, and keratoplasty. There has not been a consensus on the choice of the treatment procedure, although more recently, cultivated SC transplantation has been shown to be a promising treatment modality in the management of LSCD. This review aims to give the readers up-to-date information on LSCD.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
