Abstract

The steady-state human respiratory system was simulated with the aid of a digital computer and a Calcomp model 565 digital plotter. Equations of the model were divided into a controlling system and a controlled system. The classical controller equation of Gray (1950) was compared to the more recent work of Lloyd and Cunningham (1963). Simulation results for alveolar carbon dioxide and oxygen partial pressures as functions of a wide range of alveolar ventilation are presented (controlled system). Simulation results for alveolar ventilation, tidal volume, and respiratory frequency as functions of a wide range of alveolar carbon dioxide and oxygen partial pressures are also presented (controlling system). Similarly, simulation results for alveolar ventilation, tidal volume, and respiratory frequency are presented for a wide range of inspired carbon dioxide and oxygen partial pressures (complete model).

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