Abstract
Constructing a reasonable model to describe the motion of organelles and vesicles moved by motor proteins in cells is not straightforward but may assist in understanding the mechanism. Recently, Muller, Klumpp and Lipowsky (PNAS 105, 4609-14, 2008) have developed a tug-of-war model to describe this motion. Their model exhibits several qualitatively different motility regimes that depend on the precise value of the single motor parameters. They suggested that parameter variation could be used by a cell to regulate its cargo traffic.
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