Abstract
Because of increased need to tissue and organ transplantation, tissue engineering (TE) researches have significantly increased in recent years in Iran. The present study explored briefly the advances in the TE approaches in Iran. Through comprehensive search, we explored main TE components researches include cell, scaffold, growth factor and bioreactor conducted in Iran. The field of TE and regenerative medicine in Iran dates back to the early part of the 1990 decade and the advent of stem cell researches. During past two decades, Iran was one of leader in stem cell research in Middle East. The next major step in TE was application and fabrication of scaffolds for TE in the early 2000s with focused on engineering bone and nerve tissue. Iranian researchers extensively used natural scaffolds in their studies and hybridized natural polymers and inorganic scaffolds. There are many universities and government research institutes are conducting active research on tissue-engineering technologies. Limitations to TE in Iran include property design and validation of bioreactors. In conclusion, in the last few years, fields of tissue engineering and regenerative medicine such as stem cell technology and scaffolds have progressed in Iran, but one of the biggest challenges for TE is bioreactors researches.
Highlights
Because of increased mean life expectancy, Road traffic injuries (RTIs) and disabilities resulted from Iran-Iraq war the loss and damage of tissue is a great challenge for public health of Iran [1].Road traffic injuries (RTIs) are a major global public health problem [2,3,4]
We explored main tissue engineering (TE) components researches include cell, scaffold, growth factor and bioreactor conducted in Iran
Since Iran is one of leader in stem cell research in Middle East here, we review most stem cells used by Iranian researchers
Summary
Because of increased mean life expectancy, Road traffic injuries (RTIs) and disabilities resulted from Iran-Iraq. War the loss and damage of tissue is a great challenge for public health of Iran [1]. Road traffic injuries (RTIs) are a major global public health problem [2,3,4]. In 2005, 500,000 Iranians injured annual in road traffic crashes, and the death and injury rate is the highest of any country in the world for which reliable estimates are available [5,6]. 8-year of the Iran-Iraq war victims are another great challenge for public health of Iran. Biomedical research activities such as TE in Iran have significantly increased in recent years. Various sources of funding especially through the Iranian government in the recent years have been influential in increasing TE /biomedical researches
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