Status of Biochemical and Hematological Changes in Pregnant Malaria Patients and Pregnant Nonmalaria Women

Abstract

Background: Malaria, a condition that affects immunological responsiveness, appears to interfere with immune processes during pregnancy. During pregnancy, females are especially vulnerable to illnesses, which can have catastrophic repercussions for both the mother and the fetus. Materials and Methods: A total of 64 participants out of which 32 pregnant nonmalaria participants in Group A and 32 pregnant malaria participants in Group B. The study included participants between 20 and 42 years of age. Participants presenting with the symptoms of malaria such as headache, fever, weakness, and nausea were included. Results: The hematological parameters among the study participants. The mean transferrin level in Group A and Group B was 3.42 ± 1.26 and 4.86 ± 2.37 [Figure 1]. There was a significant difference between the two groups. The total iron-binding capacity and serum iron also showed a significant difference between the two groups. The transferrin saturation in Group A was 25.6 ± 8.51 and in Group B was 26.24 ± 5.61. There was no significant difference in the transferrin saturation and hemoglobin levels between the groups. Conclusion: Hematological and biochemical indicators may be effective in detecting malaria in pregnant women with parasites deep in tissues that are difficult to identify using a microscope.