Abstract
The present investigation was undertaken to study status of erythrocytic antioxidant enzymes in normal cycling and α- tocopherol supplemented anestrus buffalo heifers. The pre-supplementation erythrocytic activities of superoxide dismutase (U/mg Hb), glutathione peroxidase (U/mg Hb) and glucose-6-phosphate dehydrogenase (U/g Hb) upregulated significantly (p<0.05) in anestrus heifers (10.08±0.09, 14.09±0.54, 9.25±0.29) when compared to normal cycling ones (6.93±0.04, 11.61±0.19, 5.58±0.26). The oral supplementation of α-tocopherol @ 3,000 mg per week per animal in anestrus heifers declined erythrocytic superoxide dismutase and glucose-6-phosphate dehydrogenase activities significantly (p<0.01) but led to non-significant increase in erythrocytic glutathione peroxidase activity. Results indicated that supplementation of α-tocopherol to anestrus buffalo heifers mitigated the effects of oxidative stress to improve their antioxidant status. (Asian-Aust. J. Anim. Sci. 2003. Vol 16, No. 2 : 217-221)
Highlights
MATERIALS AND METHODSOxidative stress, caused by increased formation of free radicals and reactive oxygen species (ROS) through different metabolic processes and in response to exogenous stimuli, is controlled by various antioxidant defense mechanisms including antioxidant enzymes (Rock et al, 1996)
Supplementation of α-tocopherol, decreased erythrocytic SOD activities significantly (p
The increased activities of erythrocytic SOD in anestrus heifers could be attributed to physiological upregulation of this enzyme in an attempt to mitigate superoxide radical challenge
Summary
MATERIALS AND METHODSOxidative stress, caused by increased formation of free radicals and reactive oxygen species (ROS) through different metabolic processes and in response to exogenous stimuli, is controlled by various antioxidant defense mechanisms including antioxidant enzymes (Rock et al, 1996). ABSTRACT : The present investigation was undertaken to study status of erythrocytic antioxidant enzymes in normal cycling and αtocopherol supplemented anestrus buffalo heifers. The pre-supplementation erythrocytic activities of superoxide dismutase (U/mg Hb), glutathione peroxidase (U/mg Hb) and glucose-6-phosphate dehydrogenase (U/g Hb) upregulated significantly (p
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
