Abstract
Although osteosarcoma is the most common malignant bone tumor, its annual incidence is only three per million. Before the 1970s, the prognosis of osteosarcoma was very poor. With the advancement of comprehensive treatments such as chemotherapy, the prognosis of osteosarcoma has been significantly improved. This article attempts to review the development of osteosarcoma treatment in the world, the development of comprehensive treatment in China, the standardization process and the treatment prospects, and hope to present the readers the history and current status of osteosarcoma in China, and the future development as well. Key words: Osteosarcoma; Neoadjuvant therapy; Chemotherapy, adjuvant; Surgical procedures, operative
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