Abstract
ED 50 values and potency ratios are often used as if they were constants of the compounds involved. It is well known that these statistics, far from being constant, are highly dependent on the technical details of the pharmacological method. Using the estimation of mydriatic potency as an example, the author shows that the conventional measures of potency also may vary considerably according to the statistical design of the experiments.
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More From: Journal of Pharmaceutical Sciences (Scientific Edition)
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