Abstract

Objectives - statistical estimation of the physiological limits of the quantitative distribution of ethanol in cadaveric blood and bladder urine and development of an automated method for diagnosing postmortem artifacts of forensic medical examination of acute alcohol intoxication on the corpse. Material and methods. We performed a retrospective statistical analysis of the results of toxicological determination of ethanol concentration in a blood and in the urine in 2376 deaths from acute alcohol intoxication. Results. Regression equations have been developed that allow us to determine the physiological limits of the quantitative distribution of ethanol in blood and urine with any confidence probability for any degree of alcohol intoxication and phase of acute alcohol intoxication. The set of computational procedures is implemented in the format of the computer program "Alcohol calculator Z 3.0". Conclusion. If the concentrations of ethanol in the blood or in the urine are beyond their physiological limits, the results of toxicological analysis should be considered as a postmortem artifact.

Highlights

  • If the concentrations of ethanol in the blood or in the urine are beyond their physiological limits, the results of toxicological analysis should be considered as a postmortem artifact

  • 2. При концентрациях этанола в крови или в моче, выходящих за свои физиологические пределы, результаты химико-токсикологического анализа (ХТА) следует считать артефактом ввиду экзогенного загрязнения указанных биосред этанолом либо посмертных процессов новообразования или распада этанола, либо наличия технических или инструментальных погрешностей ХТА

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Summary

Introduction

Nedugov – PhD, assistant of the Department of forensic medicine. Ardashkin – PhD, Associate Professor, the Head of the Department of forensic medicine. Поэтому одной из актуальных научных проблем в судебной медицине является разработка способов диагностики посмертных артефактов определения концентрации этанола в трупной крови или моче [5,6,7].

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