Statistical Assessment of Hyperpepsinogenemia Data

Abstract

Letters and Corrections1 August 1980Statistical Assessment of Hyperpepsinogenemia DataANTONY R. UNWIN, M.D.ANTONY R. UNWIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-2-377_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: I was asked as a statistician to look at the paper by Rotter and colleagues (1) in your September 1979 issue. The medical side of the article was interesting, but I have had some doubts about the handling of data and presentation of results. In Table 1 (p. 374) the definite hyperpepsinogenemic group includes 93 affected patients (that is, those with a duodenal ulcer or an elevated pepsinogen level, or both). In Table 2 (p. 375) subset 2 "is equivalent to the entire definite hyperpepsinogenemic group" but only includes 83 affected patients. What is the reason for...Reference1. ROTTERPETERSENSAMLOFF JGI. Genetic heterogeneity of hyperpepsinogenemic I and normopepsinogenemic I duodenal ulcer disease. Ann Intern Med. 1979;91:372-7. LinkGoogle Scholar1. ROTTERPETERSENSAMLOFF JGI. Genetic herogeneity of hyperpepsinogenemic I and normopepsinogenemic I duodenal ulcer disease. Ann Intern Med. 1979;91:372-7. LinkGoogle Scholar2. HODGEROTTERLANGE SJK. A three-allele model for heterogeneity of juvenile onset insulin-dependent diabetes. Ann Hum Genet. 1980;43:399-412. CrossrefMedlineGoogle Scholar3. ROTTERRIMOINSAMLOFF JDI. Genetic heterogeneity in peptic ulcer. Lancet. 1979;1:1088-9. CrossrefMedlineGoogle Scholar4. FEINSTEIN A. Clinical Biostatistics. St. Louis: C. V. Mosby; 1977. CrossrefGoogle Scholar5. ROTTERSONESSAMLOFF JJI. Duodenal-ulcer disease associated with elevated serum pepsinogen I: an inherited autosomal dominant disorder. N Engl J Med. 1979;300:63-6. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Dublin Dublin Ireland PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 August 1980Volume 93, Issue 2Page: 377-378KeywordsDuodenal ulcersStatistical data Issue Published: 1 August 1980 PDF DownloadLoading ...