Abstract
Cancer is now the main cause of increasing mortality throughout the world. Minor alterations in the cell cycle which are inherited and not removed by apoptosis are important risk factors. Blood cancers are asmong the types which most readily cause death. Here in this study, usual but important factors such as age, gender, Rh and ABO blood typing, weight, and platelet counts are analyzed for impact on blood cancers. Frequencies and distributions, correlations and chi-square test were utilized in order to clarify the perspective of important factors. Our statistical results show males and females to have same risk in blood cancer but A blood type (40%) along with positive Rh (73%) had the highest risk. Low platelet counts are related to more than 80% of cases. Obesity has a statistically ignorable role in blood cancer prevalence. The fact that blood cancer cases increase during the second decade of life (45.7%) which might be because of involvement of maturation processes.
Highlights
Cancer is the main cause of increasing mortalities in the developing world
Some important and statistically abundant blood cancer types are acute myelogenous leukemia (AML which is known as ANLL too), Chronic Myelogenous Leukemia (CML), Chronic Lymphocytic Leukemia (CLL) and Acute Lymphocytic Leukemia (ALL) (Löwenberg 2003; World Health Organization 2009)
This study focuses on analysis of some statistically important factors such as age, gender, weight, blood groups, plaque counts, and locations which could be related to generation of blood cancers (Nishi et al, 1996; Zand et al, 2010)
Summary
Cancer is the main cause of increasing mortalities in the developing world. Cancers are usually caused by alterations within signaling pathways of specific cell lines or malfunctions of genetic materials of these cells (Ron et al, 1994; Jemal et al, 2008). Malignant cancer forms often spread through blood vessels into various body organs. This process is technically called metastasis (American Cancer Society, 2011). Cancerous cells are immature unscreened white blood cells which are produced in high numbers by bone marrow stem cells (Sandler 1995; Jackson et al, 1999). This kind of cancer can be divided into different subtypes according to its origin and emerged cell types. Often chemotherapy or radiotherapy is prescribed for such diseases but in less severe cases bone marrow stem cell transplantation is utilized (Jackson et al, 1999)
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