Statistical analysis of the radial segmentation of lymphocyte and monocyte nuclei in vitro.

Abstract

In previous studies the radial segmentation of lymphocytes and monocytesin vitro has been associated to a contraction of intermitotic residues of the mitotic spindle, parallel to a slow dissociation of cytoplasmic microtubules. In the present study it is demonstrated that the frequency distribution of radial segmented nuclei after incubationin vitro is skew and can probably not be approximated to any classical distribution. These facts form the rationale for evaluating experiments on radial segmentation by means of nonparametric statistics.