Abstract
Calcium phosphate was obtained by a semicontinuous wet process using the conventional double decomposition method between an aqueous calcium nitate solution, Ca(NO33)2, and an aqueous ammonium phosphate solution, (NH4)2HPO4. To check the effet of certain variables on the reaction, a fractional central composite design was set up taking five variables into account: pH, (Ca/P)reagents, concentration of the calcium nitrate solution ([Ca2+]). temperature (T) and duration of precipitation (D). The limiting factors of precipitation for apatitic tricalcium phosphate are discussed
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